PICO/CAT Table

PA-Port 1

1 In elderly patients with recurrent pleural effusions, is therapeutic thoracentesis preferred over surgical intervention for maintaining optimal quality of life?
2In asymptomatic patients with Wolf-Parkinson-White syndrome is catheter ablation preferred over pharmacologic intervention for management of the condition?
3In patients diagnosed with chronic obstructive pulmonary disease (COPD), does hyperbaric oxygen therapy compared to traditional oxygen therapy enhance the ability of patients with COPD to exercise at a higher exercise intensity?
4In patients diagnosed with benign prostatic hypertrophy are alpha 1 adrenergic agonists more effective than Saw Palmetto at alleviating symptoms of urinary retention?
5In patients with a history of pilonidal cysts is excision preferred over conservative treatment for management of symptoms?
6In patients diagnosed with mild-moderate asthma, is the use of a SABA/ICS during asthma flare-ups more likely to result in adverse outcomes compared to the use of ICS-Formoterol?

Mini-CAT#1: In patients with Parkinson’s disease, does Deep Brain Stimulation compared to medical management with levodopa improve motor symptoms and ability to perform activities of daily living?

PA-Port 2

1In patients undergoing hernia repair surgery, does the administration of prophylactic antibiotics versus no antibiotics reduce the incidence of postoperative complications such as surgical site infections?
2In patients with varicose veins, is sclerotherapy better at preventing recurrence of varicosities compared to endovenous ablation?
3In patients who undergo uncomplicated surgical procedures, is the use of topical antibiotics versus topical over the counter ointments more effective at promoting wound healing and reducing postoperative complications?

Mini-CAT #2: In adult smokers seeking to quit, how does nicotine replacement therapy compare to varenicline in terms of smoking cessation rates/long-term abstinence?

PA-Port 3

1In women w/ symptomatic fibroids, does the use of a hormonal intrauterine device (IUD) compared to oral contraceptives result in greater reduction in menstrual bleeding and overall improvement in fibroid-related symptoms such as heavy menstrual bleeding, dyspareunia, or dyschezia?
2In patients with a history of preterm birth, is the use of vaginal progesterone more effective than cervical cerclage in reducing the incidence of preterm birth in future pregnancies?
3In pregnant women, how does vaping/electronic cigarette use during pregnancy compared to not using vapes or electronic cigarettes affect fetal outcomes?

CAT#3: In post-menopausal women, how does use of vaginal estrogen versus no treatment affect rates of vaginitis and UTI?

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